Volume 7, Issue 1 (3-2020)                   J Jiroft Univ Med Sci 2020, 7(1): 285-291 | Back to browse issues page

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shahin jahromy S, abbassi daloii A, barari A, Saeidi A. The effect of aerobic training with two types of normal and high cholesterol diet on antioxidant and cardiac oxidative stress in male rats. J Jiroft Univ Med Sci 2020; 7 (1) :285-291
URL: http://journal.jmu.ac.ir/article-1-347-en.html
The effect of aerobic training with two types of normal and high cholesterol diet on antioxidant and cardiac oxidative stress in male rats
Susan Shahin jahromy1 , Asieh Abbassi daloii 2, Alireza Barari1 , Ayoub Saeidi3
1- Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
2- Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran , abbasi.daloii@gmail.com
3- Department of Physical Education, Damghan Branch, Islamic Azad University, Damghan, Iran.
Abstract:   (2831 Views)
Introduction: Obesity and cardiovascular disease are among the leading causes of mortality in the world. The aim of the present study was to determine the effect of aerobic training on some antioxidant and cardiac oxidative stress in male rats with two types of normal and cholesterol-rich diet.
Materials and Methods: 40 male Wistar rats randomly divided into four groups of normal-control, normal-exercise, cholesterol-rich and cholesterol-exercises. The training groups performed 12 weeks (5 days a week) of endurance training. Prior to the beginning of the training period, the cholesterol-rich diet group rats were fed this diet for three months to induce hyperlipidemia and dietary intervention was administered until the end of the training period. 48 hours after the last training session, they were killed and then their heart tissues were separated and the experiments were performed.
Results: Between groups analyses indicated a significant difference between groups consuming cholesterol and normal foods in the MDA (P = 0.001), TAC (P = 0.004) and glutathione (P = 0.013).
Conclusion: The results of this study showed that moderate-intensity aerobic activity improved oxidative stress indices and increased TAC in the hearts of mice with normal and high cholesterol diet.
Keywords: Aerobic exercise, Antioxidant, Oxidative stress, High cholesterol diet, Normal diet
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Type of Study: Research | Subject: Medical Sciences / Sports Medicine
Received: 2020/01/18 | Accepted: 2020/01/18 | Published: 2020/04/5
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