Volume 9, Issue 2 (8-2022)
J Jiroft Univ Med Sci 2022, 9(2): 968-981 |
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Dolati-Somarin A, Sabbghziarani F, Abd-Nikfarjam B. Achievements, Challenges and Efficacy of COVID-19 Vaccines: A Review Study. J Jiroft Univ Med Sci 2022; 9 (2) :968-981
URL: http://journal.jmu.ac.ir/article-1-617-en.html
URL: http://journal.jmu.ac.ir/article-1-617-en.html
1- MSc in Immunology, Department of Immunology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2- Assistant Professor of Anatomy, Department of Anatomy, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
3- Assistant Professor of Immunology, Department of Immunology, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran , nikfarjamm@gmail.com
2- Assistant Professor of Anatomy, Department of Anatomy, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
3- Assistant Professor of Immunology, Department of Immunology, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran , nikfarjamm@gmail.com
Abstract: (1305 Views)
| Introduction: Studies indicate that vaccination is the most effective method of preventing infection with COVID-19. The purpose of this study is to provide vaccination considerations of patients with autoimmune/autoinflammatory rheumatologic diseases, immunodeficiencies, cancer, diabetes, chronic respiratory, and cardiovascular diseases for doctors, healthcare staff, and patients.. Materiala and Methods: In this review study, a search was done in scientific electronic databases such as ISI, Google scholar, Scopus, and PubMed. The most up-to-date, relevant, and reliable articles published in 2019-2022 were used on the topic of COVID-19 vaccines and vaccination of patients with certain diseases. Results: Patients with autoimmune diseases should be vaccinated against COVID-19 when the disease activity is under control and there is no co-infection. Mild immunosuppression does not reduce the antibody response to vaccines. Vaccination with all types of vaccines except for live attenuated vaccines is effective for all cancer patients, with the exception of those receiving anti-B cell therapy. Moreover, vaccination of individuals with comorbidities (obesity, cardiovascular diseases, respiratory diseases, and diabetes) which increase the risk of severe COVID-19 is recommended. Conclusion: The best way to deal with the SARS-CoV-2 virus is to increase vaccination coverage to induce immune responses against this virus. It is recommended that patients with immune system defects, people who take immunosuppressive drugs, and the elderly receive booster doses of the Corona vaccine. |
Type of Study: Review |
Subject:
Medical Sciences / Immunology and Biology
Received: 2022/06/15 | Accepted: 2022/09/3 | Published: 2022/09/21
Received: 2022/06/15 | Accepted: 2022/09/3 | Published: 2022/09/21
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