Volume 5, Issue 2 (3-2019)                   J Jiroft Univ Med Sci 2019, 5(2): 75-86 | Back to browse issues page

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Antifungal Susceptibility of Candida Species Isolated from Admitted Patients with Candiduria in Amir Al-Momenin Hospital, Zabol . J Jiroft Univ Med Sci. 2019; 5 (2) :75-86
URL: http://journal.jmu.ac.ir/article-1-241-en.html
Abstract:   (1574 Views)
Antifungal Susceptibility of Candida Species Isolated from Admitted Patients
with Candiduria in Amir Al-Momenin Hospital, Zabol

 
Mojtaba Hoseinpoor (MD)1, Zahra Rashki Ghalehnoo (PhD)2*, Omid Tadjrobehkar (PhD)3
1MD, Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran
2Assistant professor of Microbiology and Molecular Genetics, Department of Microbiology,
Faculty of Medicine, Zabol University of Medical Sciences, Zabol, Iran
3Assistant professor of Medical Microbiology, Department of Microbiology and
Virology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
Received: 15 oct. 2018    Accepted: 18 Jan.2019

Introduction: Candida albicans (C. albicans) is an opportunistic fungal pathogen that causes a wide range infections in human and animals. Although C. albicans is major pathogenic species, but other Candida species such as C. glabrata, C. tropicalis and C. krusei have been isolated from patients. Identification of Candida species is essential for effective antifungal therapy and for infection control purposes. The aim of the present study was to detect the frequency of Candiduria and to evaluate the antifungal susceptibility profile of candida isolates collected from admitted patients in Zabol University teaching Hospital.
Methods: This cross-sectional study was performed on 157 urine samples. All recovered isolates were identified by using CHRO Magar Candida medium and routine laboratory procedure. Then antifungal susceptibility testing was performed by disk diffusion method.
Results: A total of 48 (31%) isolates of Candida species were recovered from 157 urine samples. C. albicans was the most prevalent species 37.5%, followed by C. tropicalis (31.25%) and C. krusei (31.25%). Antifungal susceptibility test indicated that 96% and 90% of the Candida isolates were susceptible to amphotericin B and econazole, respectively.
Conclusion: The present study reiterates the prevalence of Candida species among candiduria and their antifungal susceptibility pattern. Prevalence of C. albicans was more than other Candida species. Candida species are more susceptible to amphotericin B and econazol. Therefore, identification of candida species along with their antifungal susceptibility pattern can help to clinicians in better treating the patients with candiduria.
  

Please cite this article as follows:
Hoseinpoor M, Rashki Ghalehnoo Z, Tadjrobehkar O. Antifungal Susceptibility of Candida Species Isolated from admitted Patients with Candiduria in Amir al-momenin hospital, Zabol. 2018; 1 (3): 75-86

 

 
 
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Type of Study: Research | Subject: Medical Sciences / Microbiology
Received: 2019/02/10 | Accepted: 2019/02/10 | Published: 2019/02/10

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