1. George P. Concerns regarding the safety and toxicity of medicinal plants-An overview. Journal of Applied Pharmaceutical Science. 2011:40-4.
2. Posadzki P, Watson LK, Ernst E. Adverse effects of herbal medicines: an overview of systematic reviews. Clinical Medicine. 2013;13(1):7. [
DOI:10.7861/clinmedicine.13-1-7]
3. Carmona F, Pereira AMS. Herbal medicines: old and new concepts, truths and misunderstandings. Revista Brasileira de Farmacognosia. 2013;23:379-85. [
DOI:10.1590/S0102-695X2013005000018]
4. Abdollahi M, Soltaninejad K. A review on toxicity of plants in human. Journal of Medicinal Plants. 2002;1(3):1-12.
5. Verma H, Silakari O. Benzoxazolinone: A scaffold with diverse pharmacological significance. Key Heterocycle Cores for Designing Multitargeting Molecules: Elsevier; 2018.343-67. [
DOI:10.1016/B978-0-08-102083-8.00010-8]
6. Atmakuri LR, Dathi S. Current trends in herbal medicines. Journal of Pharmacy Research. 2010;3(1):109-13.
7. Amoli JS, Sadighara P, Barin A, Yazdani A, Satari S. Biological screening of Amaranthus retroflexus L.(Amaranthaceae). Revista Brasileira de Farmacognosia. 2009;19(2B):617-20. [
DOI:10.1590/S0102-695X2009000400019]
8. Assarehzadegan MA, Sankian M, Jabbari F, Noorbakhsh R, Varasteh A. Allergy to Salsola Kali in a Salsola incanescens-rich area: role of extensive cross allergenicity. Allergology International. 2009;58(2):261-6. [
DOI:10.2332/allergolint.08-OA-0041]
9. Khan MN, Jan A. Evaluation of pharmacognostic features and antimicrobial activities of Dysphania botrys L. Sarhad Journal of Agriculture. 2019;35(4) 1234-42. [
DOI:10.17582/journal.sja/2019/35.4.1234.1242]
10. Khare CP. Indian medicinal plants: an illustrated dictionary: Springer Science & Business Media; 2008. [
DOI:10.1007/978-0-387-70638-2]
11. Amjad L. Comparative study of pollen extracts allergenicity of Chenopodium album L. and Chenopodium botrys L. an in vivo study. Inter Proceed Chemic Biol Environ Engin. 2009;5:338-41.
12. Kokanova-Nedialkova Z, Nedialkov P, Nikolov S. The genus Chenopodium: phytochemistry, ethnopharmacology and pharmacology. Pharmacognosy Reviews. 2009;3(6):280.
13. Nagle D, Mahdi F, Datta S, Li J, Du L, Smillie T, et al. Assessing the Potential Mitochondrial-Mediated Toxicity of Herbal Dietary Supplements. Planta Medica. 2011;77(05): 11. [
DOI:10.1055/s-0031-1273513]
14. Khan MN. Phytochemical and pharmacological profiling of dysphania botrys: The University of Agriculture, Peshawar.; 2019.
15. Khazaei S, Abdul Hamid R, Ramachandran V, Mohd Esa N, Pandurangan AK, Danazadeh F, et al. Cytotoxicity and Proapoptotic Effects of Allium atroviolaceum Flower Extract by Modulating Cell Cycle Arrest and Caspase-Dependent and p53-Independent Pathway in Breast Cancer Cell Lines. Evidence-Based Complementary and Alternative Medicine. 2017 (1): 1468957. [
DOI:10.1155/2017/1468957]
16. Jonkers D, Sluimer J, Stobberingh E. Effect of garlic on vancomycin-resistant enterococci. Antimicrobial Agents and Chemotherapy. 1999;43(12):3045 [
DOI:10.1128/AAC.43.12.3045]
17. Dhivya P, Sobiya M, Selvamani P, Latha S. An approach to Alzheimer's disease treatment with cholinesterase inhibitory activity from various plant species. International Journal of PharmTech Research. 2014;6(5):1450-67.
18. Akhondzadeh S, Noroozian M. Alzheimer's disease: pathophysiology and pharmacotherapy. IDrugs: the investigational drugs journal. 2002;5(11):1062-9.
19. Rivera R, Antognini JF. Perioperative drug therapy in elderly patients. Anesthesiology: The Journal of the American Society of Anesthesiologists. 2009;110(5):1176-81. [
DOI:10.1097/ALN.0b013e3181a10207]
20. Mokhtarpour A, Naserian AA, Valizadeh R, Mesgaran MD, Pourmollae F. Extraction of phenolic compounds and tannins from pistachio by-products. Annual Research & Review in Biology. 2014:1330-8. [
DOI:10.9734/ARRB/2014/7793]
21. Hehmann M, Lukačin R, Ekiert H, Matern U. Furanocoumarin biosynthesis in Ammi majus L. European Journal of Biochemistry.2004 03/01;271:932-40. [
DOI:10.1111/j.1432-1033.2004.03995.x]
22. Stern RS. The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: A 30-year prospective study. Journal of the American Academy of Dermatology. 2012;66(4):553-62. [
DOI:10.1016/j.jaad.2011.04.004]
23. Selim YA, Ouf NH. Anti-inflammatory new coumarin from the Ammi majus L. Organic and medicinal chemistry letters. 2012;2(1):1. [
DOI:10.1186/2191-2858-2-1]
24. Al-Snafi AE. Encyclopedia of the constituents and pharmacological effects of Iraqi medicinal plants: Rigi Publication; 2015.
25. Nimrouzi M, Zarshenas MM. Holistic approach to functional constipation: Perspective of traditional Persian medicine. Chinese journal of integrative medicine. 2019;25(11):867-72. [
DOI:10.1007/s11655-015-2302-3]
26. Monsefi M, Zahmati M, Masoudi M, Javidnia K. Effects of Anethum graveolens L. on fertility in male rats. The European Journal of Contraception & Reproductive Health Care. 2011;16(6):488-97. [
DOI:10.3109/13625187.2011.622815]
27. Esmaeilzadeh M, Moradi B. Medicinal herbs with side effects during pregnancy-An evidence-based review article. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2017 22(20):9-25 (in Persion).
28. Rouhi-Boroujeni H, Gharipour M, Mohammadizadeh F, Ahmadi S, Rafieian-Kopaei M. Systematic review on safety and drug interaction of herbal therapy in hyperlipidemia: a guide for internist. Acta bio-medica: Atenei Parmensis. 2015;86(2):130-6.
29. Khairuddin H, Qazvinian KH, Medicinal and aromatic plants, their characteristics and mportance, Samangan Publications, 1390 (book, in persion).
30. Stefanie Sausenthaler SK, Beate Schaaf, Irina Lehmann, Michael Borte, Olf Herbarth, Andrea von Berg,, H-Erich Wichmann aJH. Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 y of age. The American journal of clinical nutrition. 2007;85(2):530-7. [
DOI:10.1093/ajcn/85.2.530]
31. Jones AF. PERFORATION OF SMALL INTESTINE BY CELERY. Canadian Medical Association journal. 1950;63(3):291.
32. Modaresi M, Ghalamkari G. The effect of celery (Apium graveolens) extract on the reproductive hormones in male mice. APCBEE Procedia. 2012;4:99-104. [
DOI:10.1016/j.apcbee.2012.11.017]
33. Khalighi Sigaroodi F, Jarvandi S, Taghizadeh M. Interactions of herbs with conventional drugs (Section 2). Journal of Medicinal Plants. 2003;4(8):1-16.
34. Bahmani M, Eftekhari Z, Jelodari M, Saki K, Abdollahi R, Majlesi M, et al. Effect of Iranian herbal medicines in dysmenorrhea phytotherapy. Journal of Chemical and Pharmaceutical Research. 2015 (2):519-26.
35. Siska S, Munim A, Bahtiar A, Suyatna FD. Effect of Apium graveolens Extract Administration on the Pharmacokinetics of Captopril in the Plasma of Rats. Scientia pharmaceutica. 2018;86(1):6. [
DOI:10.3390/scipharm86010006]
36. Johri R. Cuminum cyminum and Carum carvi: An update. Pharmacognosy reviews. 2011;5(9):63. [
DOI:10.4103/0973-7847.79101]
37. Rodriguez-Fragoso L, Reyes-Esparza J, Burchiel SW, Herrera-Ruiz D, Torres E. Risks and benefits of commonly used herbal medicines in Mexico. Toxicology and applied pharmacology. 2008;227(1):125-35. [
DOI:10.1016/j.taap.2007.10.005]
38. Lovell C, Paulsen E, Lepoittevin J-P. Adverse Skin Reactions to Plants and Plant Products. Contact Dermatitis. 2020:1-49. [
DOI:10.1007/978-3-319-72451-5_88-2]
39. Choudhary N, Khajuria V, Gillani ZH, Tandon VR, Arora E. Effect of Carum carvi, a herbal bioenhancer on pharmacokinetics of antitubercular drugs: A study in healthy human volunteers. Perspectives in clinical research. 2014;5(2):80. [
DOI:10.4103/2229-3485.128027]
40. Chanda S, Rakholiya K. Combination therapy: Synergism between natural plant extracts and antibiotics against infectious diseases. Microbiol Book Series. 2011;1:520-9.
41. Khoram Z, Naine A, Rafieinezha R, Hakimaneh SM, Hakimaneh SMR, Shayehg SS, et al. The Antifungal Effects of Two Herbal Essences in Comparison with Nystatin on the Candida Strains Isolated from the Edentulous Patients. Journal of Contemporary Dental Practice. 2019;20(6). [
DOI:10.5005/jp-journals-10024-2585]
42. Mehdipour M, Gholizadeh N, Sadrzadeh-Afshar M-S, Hematpoor N, Kalaee P, Hakemi Vala M, et al. In Vitro Comparison of the Efficacy of Cumin Extract and Fluconazole Against Candida Strains. Journal of Islamic Dental Association of Iran. 2019;31(2):98-108. [
DOI:10.30699/jidai.31.2.98]
43. Gavanji S, Zaker SR, Nejad ZG, Bakhtari A, Bidabadi ES, Larki B. Comparative efficacy of herbal essences with amphotricin B and ketoconazole on Candida albicans in the in vitro condition. Integrative medicine research. 2015;4(2):112-8. [
DOI:10.1016/j.imr.2015.01.003]
44. Scheie AA. Modes of action of currently known chemical anti-plaque agents other than chlorhexidine. J dent Res. 1989;68:1609-16.
45. Allahghadri T, Rasooli I, Owlia P, Nadooshan MJ, Ghazanfari T, Taghizadeh M, et al. Antimicrobial property, antioxidant capacity, and cytotoxicity of essential oil from cumin produced in Iran. Journal of food science. 2010;75(2): 54-61. [
DOI:10.1111/j.1750-3841.2009.01467.x]
46. Chaudhry Z, Khera RA, Hanif MA, Ayub MA, Sumrra SH. Cumin. Medicinal Plants of South Asia: Elsevier; 2020. p. 165-78. [
DOI:10.1016/B978-0-08-102659-5.00013-6]
47. Srinivasan K. Plant foods in the management of diabetes mellitus: spices as beneficial antidiabetic food adjuncts. International journal of food sciences and nutrition. 2005;56(6):399-414. [
DOI:10.1080/09637480500512872]
48. Shirke SS, Jadhav SR, Jagtap AG. Methanolic extract of Cuminum cyminum inhibits ovariectomy-induced bone loss in rats. Experimental Biology and Medicine. 2008;233(11):1403-10. [
DOI:10.3181/0803-RM-93]
49. Bishayee K, Mukherjee A, Paul A, Khuda-Bukhsh AR. Homeopathic mother tincture of Conium initiates reactive oxygen species mediated DNA damage and makes HeLa cells prone to apoptosis. Int J Genuine Tradit Med. 2012;2:37-41. [
DOI:10.5667/tang.2012.0018]
50. Farzaei MH, Bayrami Z, Farzaei F, Aneva I, Das SK, Patra JK, et al. Poisoning by Medical Plants. Archives of Iranian medicine. 2020;23(2):117-27.
51. Mondal J, Panigrahi AK, Khuda-Bukhsh AR. Anticancer potential of Conium maculatum extract against cancer cells in vitro: Drug-DNA interaction and its ability to induce apoptosis through ROS generation. Pharmacognosy magazine. 2014;10(Suppl 3):S524. [
DOI:10.4103/0973-1296.139792]
52. Vatanparast J, Bazleh S, Janahmadi M. The effects of linalool on the excitability of central neurons of snail Caucasotachea atrolabiata. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2017;192:33-9. [
DOI:10.1016/j.cbpc.2016.12.004]
53. Duarte A, Ferreira S, Silva F, Domingues F. Synergistic activity of coriander oil and conventional antibiotics against Acinetobacter baumannii. Phytomedicine. 2012;19(3-4):236-8. [
DOI:10.1016/j.phymed.2011.11.010]
54. Al-Snafi AE. Arabian medicinal plants for the treatment of intestinal disorders-plant based review (part 1). health. 2018;21:22.
55. Yousefzadi M, Heidari M, Akbarpour M, Mirjalili MH, Zeinali A, Parsa M. In vitro cytotoxic activity of the essential oil of Dorema ammoniacum D. Don. Middle-East J Sci Res. 2011;7(4):511-4.
56. Adhami H-R, Lutz J, Kählig H, Zehl M, Krenn L. Compounds from gum ammoniacum with acetylcholinesterase inhibitory activity. Scientia pharmaceutica. 2013;81(3):793-806. [
DOI:10.3797/scipharm.1306-16]
57. Pandpazir M, Kiani A, Fakhri S. Anti-Inflammatory effect and skin toxicity of aqueous extract of Dorema ammoniacum gum in experimental animals. Research Journal of Pharmacognosy. 2018;5(4):1-8.
58. Tavakkoli H, Derakhshanfar A, Moayedi J, Fard AP. Utilization of a chicken embryo membrane model for evaluation of embryonic vascular toxicity of Dorema ammoniacum. Avicenna Journal of Phytomedicine. 2020;10(2):152.
59. Alimohammadi B, Moslem A, Azhdari ZH, Kamranian H. The roles of opioid receptors on anticonvulsant properties of hydro alcoholic extract of scrophularia striata Boiss in mice. 2016.
60. Motevalian M, Mehrzadi S, Ahadi S, Shojaii A. Anticonvulsant activity of Dorema ammoniacum gum: evidence for the involvement of benzodiazepines and opioid receptors. Research in Pharmaceutical Sciences. 2017;12(1):53. [
DOI:10.4103/1735-5362.199047]
61. Fernández SP, Wasowski C, Loscalzo LM, Granger RE, Johnston GA, Paladini AC, et al. Central nervous system depressant action of flavonoid glycosides. European Journal of Pharmacology. 2006;539(3):168-76. [
DOI:10.1016/j.ejphar.2006.04.004]
62. Wollenweber E, Dörr M, Rustiyan A. Dorema aucheri, the first umbelliferous plant found to produce exudate flavonoids. Phytochemistry. 1995;38(6):1417. [
DOI:10.1016/0031-9422(94)00840-P]
63. Berim A, Gang DR. Methoxylated flavones: occurrence, importance, biosynthesis. Phytochemistry Reviews. 2016;15(3):363-90. [
DOI:10.1007/s11101-015-9426-0]
64. Ahmadi Koulaei S, Hadjiakhoondi A, Delnavazi MR, Tofighi Z, Ajani Y, Kiashi F. Chemical composition and biological activity of Ferula aucheri essential oil. Research Journal of Pharmacognosy. 2020;7(2):21-31.
65. Hajimehdipoor H, Ara L, Moazzeni H, Esmaeili S. Evaluating the antioxidant and acetylcholinesterase inhibitory activities of some plants from Kohgiluyeh va Boyerahmad province, Iran. Research Journal of Pharmacognosy. 2016;3(4):1-7.
66. Rajkowska K, Nowak A, Kunicka-Styczyńska A, Siadura A. Biological effects of various chemically characterized essential oils: Investigation of the mode of action against Candida albicans and HeLa cells. RSC advances. 2016;6(99):97199-207. [
DOI:10.1039/C6RA21108A]
67. Mottaghipisheh J, Nové M, Spengler G, Kúsz N, Hohmann J, Csupor D. Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia. Pharmaceutical Biology. 2018;56(1):658-64. [
DOI:10.1080/13880209.2018.1548625]
68. Ebrahimi N, Samani JE, Zolghadri JS. The effect of the hydro-alcoholic extract of (Ducrosia anethifolia) on testosterone hormone and the histological changes of the testicle in male adult rats. 2016.
69. Wang P, Su Z, Yuan W, Deng G, Li S. Phytochemical constituents and pharmacological activities of Eryngium L.(Apiaceae). 2012. [
DOI:10.2174/2210290601203010099]
70. Fazli BB, Parsaei H, Heydar ZG, Shoshtari A. Evaluation of antinociceptive and antimicrobial activities of galbanum plant (Ferula gummosa). 1997.
71. Sayyah M, Mandgary A, Kamalinejad M. Evaluation of the anticonvulsant activity of the seed acetone extract of Ferula gummosa Boiss. against seizures induced by pentylenetetrazole and electroconvulsive shock in mice. Journal of Ethnopharmacology. 2002;82(2-3):105-9. [
DOI:10.1016/S0378-8741(02)00166-6]
72. Mahboubi M, Feizabadi MM. Antimicrobial activity of some essential oils alone and in combination with amikacin against acinetobacter sp. Journal of Microbiology, Biotechnology and Food Sciences. 2020;9(5):412-5. [
DOI:10.15414/jmbfs.2016.5.5.412-415]
73. Iranshahi M, Barthomeuf C, Bayet-Robert M, Chollet P, Davoodi D, Piacente S, et al. Drimane-type sesquiterpene coumarins from Ferula gummosa fruits enhance doxorubicin uptake in doxorubicin-resistant human breast cancer cell line. Journal of Traditional and Complementary Medicine. 2014;4(2):118-25. [
DOI:10.4103/2225-4110.126181]
74. Soltani S, Amin G, Salehi-Sourmaghi MH, Iranshahi M. Histone deacetylase inhibitory and cytotoxic activities of the constituents from the roots of three species of Ferula. Iranian Journal of Basic Medical Sciences. 2019;22(1):93.
75. Farhadi F, Soltani S, Saberi S, Iranshahi M. A qHNMR method for simultaneous quantification of terpenoids from Ferula ovina (Boiss.) Boiss roots. Journal of Pharmaceutical and Biomedical Analysis. 2019;172:120-5. [
DOI:10.1016/j.jpba.2019.04.039]
76. Hosseinzadeh N, Shomali T, Hosseinzadeh S, Raouf Fard F, Jalaei J, Fazeli M. Cytotoxic activity of Ferula persica gum essential oil on murine colon carcinoma (CT26) and Vero cell lines. Journal of Essential Oil Research. 2020;32(2):169-77. [
DOI:10.1080/10412905.2020.1729880]
77. Sattar Z, Iranshahi M. Phytochemistry and pharmacology of Ferula persica Boiss.: A review. Iranian Journal of Basic Medical Sciences. 2017;20(1):1.
78. Karimi G, Iranshahi M, Hosseinalizadeh F, Riahi B, Sahebkar A. Screening of acetylcholinesterase inhibitory activity of terpenoid and coumarin derivatives from the genus Ferula. Pharmacologyonline. 2010;1:566-74.
79. Zengin S, Oktay MM, Kamalak M, Al B, Yildirim C, Buyukaslan H. Acute hepatitis associated with the use of herbal tea (Fennel and cumin). Journal of Clinical and Analytical Medicine 2015;6(6):781-3.
80. Okdemir D, Hatipoglu N, Kurtoglu S, Akın L, Kendirci M. Premature thelarche related to fennel tea consumption? Journal of Pediatric Endocrinology and Metabolism. 2014;27(1-2):175-9. [
DOI:10.1515/jpem-2013-0308]
81. Boltman H. A systematic review on maternal and neonatal outcomes of ingested herbal and homeopathic remedies used during pregnancy, birth and breastfeeding: University of the Western Cape; 2005.
82. Ostad S, Khakinegad B, Sabzevari O. Evaluation of the teratogenicity of fennel essential oil (FEO) on the rat embryo limb buds culture. Toxicology in Vitro. 2004;18(5):623-7. [
DOI:10.1016/j.tiv.2004.02.008]
83. Tariq A, Adnan M, Iqbal A, Sadia S, Fan Y, Nazar A, et al. Ethnopharmacology and toxicology of Pakistani medicinal plants used to treat gynecological complaints and sexually transmitted infections. South African Journal of Botany. 2018;114:132-49. [
DOI:10.1016/j.sajb.2017.11.004]
84. Smeriglio A, Tomaino A, Trombetta D. Herbal products in pregnancy: experimental studies and clinical reports. Phytotherapy Research. 2014;28(8):1107-16. [
DOI:10.1002/ptr.5106]
85. Boullata J. Natural health product interactions with medication. Nutrition in clinical practice. 2005;20(1):33-51. [
DOI:10.1177/011542650502000133]
86. Combest W, Newton M, Combest A, Kosier JH. Effects of herbal supplements on the kidney. Urologic Nursing Journal. 2005;25(5):381-6.
87. Kisiel W, Janeczko Z, Zgud-Walaszek M. A germacradiene glycoside from roots of Pimpinella saxifraga. Phytochemistry. 1998;49(7):2031-3. [
DOI:10.1016/S0031-9422(98)00399-9]
88. Frater-Schröder M. Wirksamkeit und Verträglichkeit von Bronchosan ("Efficacy and tolerability of bronchosan"). Schweiz Zschr Ganzheits Medizin. 1995;1:34-8.
89. Elahi A, Fereidooni A, Shahabinezhad F, Ajdari Tafti M, Zarshenas M-M. An overview of amenorrhea and respective remedies in Traditional Persian Medicine. Trends in Pharmaceutical Sciences. 2016;2(1):3-10.
90. Zahri S, Razavi SM, Niri FH, Mohammadi S. Induction of programmed cell death by Prangos uloptera, a medicinal plant. Biological Research. 2009;42(4):517-22. [
DOI:10.4067/S0716-97602009000400013]
91. Johnson JA, Webster D, Gray CA. The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins. Journal of Ethnopharmacology. 2013;147(1):232-7. [
DOI:10.1016/j.jep.2013.03.009]
92. Sadraei H, Asghari G, Hajhashemi V, Nezami M. Evaluation of cardiovascular effect of Pycnocycla spinosa Decne. exBoiss. var. spinosa extract in anaesthetized rat. DARU Journal of Pharmaceutical Sciences. 2006;14(1):11-4.
93. Hajhashemi V, Sadraei H, Ghannadi AR, Mohseni M. Antispasmodic and anti-diarrhoeal effect of Satureja hortensis L. essential oil. Journal of Ethnopharmacology. 2000;71(1-2):187-92. [
DOI:10.1016/S0378-8741(99)00209-3]
94. Nordeng H, Havnen GC. Impact of socio-demographic factors, knowledge and attitude on the use of herbal drugs in pregnancy. Acta Obstetricia et Gynecologica Scandinavica. 2005;84(1):26-33. [
DOI:10.1111/j.0001-6349.2005.00648.x]
95. Sereshty M, Azari P, Rafiean M, Kheiri S. Use of herbal medicines by pregnant women in Shahr-e-Kord. Journal of Reproduction & Infertility. 2006;7(2),125-31.
96. Carmona F, Pereira AMS. Herbal medicines: old and new concepts, truths and misunderstandings. Revista Brasileira de Farmacognosia. 2013;23(2):379-85. [
DOI:10.1590/S0102-695X2013005000018]
97. Marcus DM, Grollman AP. Botanical medicines-the need for new regulations. Massachusetts Medical Society; 2002.. 2073-6. [
DOI:10.1056/NEJMsb022858]
98. Huxtable RJ. The harmful potential of herbal and other plant products. Drug Safety. 1990;5(1):126-36. [
DOI:10.2165/00002018-199000051-00020]