fa تاثیر یک دوره دویدن شدید تناوبی همراه با مصرف ویتامین D بر سطوح TSH و MCP-1 در زنان دارای اضافه وزن با نقص ویتامین D علوم پزشکی / فيزيولوژي Medical Sciences / Physiology پژوهشي Research <div> <table align="left" hspace="0" vspace="0"> <tbody> <tr> <td style="padding: 0cm 12px; text-align: justify;" valign="top"><span style="font-size:10pt"><span style="text-justify:inter-ideograph"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">مقدمه و هدف:</span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> شاخص توده بدنی بالا و نقص ویتامین </span></span>D<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> از عوامل اصلی اختلال در عملکرد تیروئید و بافت چربی محسوب می&shy; شوند. </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">هدف از مطالعه حاضر بررسی تأثیر یک دوره دویدن شدید تناوبی همراه با مصرف ویتامین </span></span>D<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بر سطوح </span></span>TSH <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">و </span></span>MCP-1 <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">در زنان </span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">اضافه وزن<b> </b></span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">دارای نقص ویتامین </span></span>D<span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بود.</span></span><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Mitra""></span></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:inter-ideograph"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">روش کار:</span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> این مطالعه نیمه تجربی بر روی 26 زن جوان دارای </span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">اضافه وزن<b> </b></span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">دارای نقص ویتامین</span></span>D<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> ، شهر بابل در سال 1400 انجام شد. </span></span>&nbsp;<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">آزمودنی ها پس از انتخاب به صورت دسترس و هدفمند، به طور تصادفی به دو گروه مداخله و کنترل تقسیم شدند. تمرین اصلی شامل 8 هفته</span></span> <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">دویدن شدید تناوبی با شدت 80-90% ضربان قلب حداکثر و یک دقیقه استراحت فعال با شدت 50% ضربان قلب حداکثر طی 8 هفته بود و ویتامین </span></span>D<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> در دوز 50000 واحد هفتگی مصرف می‌شد. سطوح سرمی </span></span>TSH <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">و </span></span>MCP-1 <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">قبل و پس از 8 هفته تعیین شد. از آزمون‌های</span></span>&nbsp; t <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">مستقل و </span></span>t<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> زوجی</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">برای آنالیز داده &shy;ها در سطح معناداری </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">0/05</span></span><span arial="" style="font-family:">></span>p<span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> استفاده شد.</span></span><b><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Mitra""></span></span></b></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:inter-ideograph"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">یافته &shy;ها:</span></span></b> <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">تجزیه‌</span></span> <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">و</span></span> <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">تحلیل داده&shy; ها نشان داد که سطوح سرمی </span></span>TSH<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> و </span></span>MCP-1<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> پس از 8 هفته در گروه مداخله کاهش معناداری </span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">داشت</span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">. همچنین اختلاف معناداری بین میانگین‌های </span></span>TSH<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> و </span></span>MCP-1<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> دو گروه مداخله و کنترل مشاهده شد(0/001></span></span>p<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">).</span></span><b><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Mitra""></span></span></b></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:inter-ideograph"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">نتیجه‌گیری:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">بر اساس نتایج پژوهش،</span></span> <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">هم‌زمانی انجام</span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> دویدن</span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> تناوبی شدید همراه و مصرف ویتامین </span></span>D<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> می&shy;تواند به افزایش سلامتی افراد دارای اضافه وزنی با نقص </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">ویتامین </span></span>D<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">، </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">به‌واسطه بهبود عملکرد تیروئیدی و کاهش شاخص التهابی </span></span>MCP-1<span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> کمک نماید.</span></span><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Mitra""></span></span></span></span></span></span></span></span></td> </tr> </tbody> </table> </div> <div style="text-align: justify;"></div> <div> <table align="center" hspace="0" vspace="0"> <tbody> <tr> <td align="left" style="padding-top:0cm; padding-right:12px; padding-bottom:0cm; padding-left:12px" valign="top"> <pre> <span style="font-size:10pt"><span style="background:white"><span style="text-justify:inter-ideograph"><span courier="" new="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Introduction</span></b><b><span new="" roman="" style="font-family:" times="">:</span></b> <span new="" roman="" style="font-family:" times=""><span style="color:#202124">High body mass index and vitamin deficiency are considered to be the main factors of thyroid and fat tissue dysfunction. The aim of the present study was to investigate the effect of a period of high intensity running training with vitamin D consumption on TSH and MCP-1 levels in overweight women with vitamin D deficiency.</span></span><span new="" roman="" style="font-family:" times=""><span style="color:#202124"></span></span></span></span></span></span></pre> <pre style="margin-top: 16px; text-align: justify;"> <span style="font-size:10pt"><span style="background:white"><span style="text-justify:inter-ideograph"><span courier="" new="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Materials </span></b><b><span new="" roman="" style="font-family:" times="">and Methods</span></b>: <span new="" roman="" style="font-family:" times="">This semi-experimental study was conducted on 26 overweight young women with vitamin D deficiency in Babol city, in 1400.</span> <span new="" roman="" style="font-family:" times="">After the accessible and purposeful selection, the subjects were randomly divided into two intervention and control groups. The main training consisted of 8 weeks of high intensity running with an intensity of 80-90% of the maximum heart rate and one minute of active rest with an intensity of 50% of the maximum heart rate during 8 weeks, and vitamin D was taken at a dose of 50,000 units weekly. Serum levels of TSH and MCP-1 were determined before and after 8 weeks. Independent t and paired t tests were used to analyze the data at a significance level of P&le;0.05.</span></span></span></span></span></pre> <div style="text-align: justify;"><span style="font-size:10pt"><span style="background:white"><span style="text-justify:inter-ideograph"><span style="line-height:normal"><span new="" roman="" style="font-family:" times=""><b>Results:</b> Data analysis showed that the serum levels of TSH and MCP-1 decreased significantly in the intervention group after 8 weeks. In addition, a significant difference in the mean of TSH and MCP-1 between the intervention and control groups was observed (p<0.001).</span></span></span></span></span></div> <div><span style="font-size:10pt"><span style="background:white"><span style="text-justify:inter-ideograph"><span style="line-height:normal"><span new="" roman="" style="font-family:" times=""><b>Conclusion:</b> Based on the results, the simultaneity of intense intermittent running and vitamin D intake can help increase the health of overweight people with vitamin D intake, by improving thyroid function and reducing the inflammatory index of MCP-1.</span></span></span></span></span></div> </td> </tr> </tbody> </table> </div> پروتئین جاذب شیمیایی مونوسیت-1, اضافه وزن, دویدن شدید, عملکرد تیروئید, ویتامین D Monocyte Chemoattractant Protein-1, Overweight, Running training, Thyroid function, Vitamin D 1489 1496 http://journal.jmu.ac.ir/browse.php?a_code=A-10-777-1&slc_lang=fa&sid=1 Maedeh Kabiri مائده کبیری 10031947532846008087 10031947532846008087 No MA of Physical Education, Department of Physical Education and Sport Sciences, Qaemshahr Branch,Islamic Azad University, Qaemshahr, Iran کارشناس ارشد فیزیولوژی ورزش، گروه تربیت بدنی، واحد قائمشهر، دانشگاه آزاد اسلامی، قائمشهر، ایران Babisan Askari بابی سان عسکری babisan.askari@gmail.com 10031947532846008088 10031947532846008088 Yes Assistant Professor, Department of Physical Education and Sport Sciences, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran استادیار فیزیولوژی ورزش، گروه تربیت بدنی، واحد قائمشهر، دانشگاه آزاد اسلامی، قائمشهر، ایران Masoumeh Habibian معصومه حبیبیان 10031947532846008089 10031947532846008089 No Associate Professor, Department of Physical Education and Sport Sciences, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran دانشیار فیزیولوژی ورزش، گروه تربیت بدنی، واحد قائمشهر، دانشگاه آزاد اسلامی، قائمشهر، ایران