fa تأثیر هشت هفته تمرین منتخب مقاومتی بر سطوح آیریزین، فولیستاتین و FGF21 در زنان بهبود یافته از کووید-19 علوم پزشکی / پزشکي ورزشي Medical Sciences / Sports Medicine پژوهشي Research <div> <table align="left" hspace="0" vspace="0"> <tbody> <tr> <td style="padding: 0cm 12px; text-align: justify;" valign="top"><span style="font-size:10pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">مقدمه و هدف:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">اخیرا انجام فعالیت&shy; های ورزشی منظم به واسطه ترشح مایوکاین&shy; ها در کاهش عوارض ناشی از کووید-19 بویژه کاهش التهاب و استرس اکسیداتیو، بازسازی و ترمیم بافت&shy; های آسیب دیده و کاهش اختلالات متابولیک مورد توجه قرار گرفته است. هدف از انجام این مطالعه تعیین</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">تأثیر هشت هفته تمرین منتخب مقاومتی بر سطوح آیریزین، فولیستاتین و فاکتور رشد فیبروبلاست 21 </span></span><span b="" mitra="" style="font-family:">(</span>FGF21<span b="" mitra="" style="font-family:">)</span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> در زنان بهبود یافته از کووید-19 بود.</span></span><b><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Mitra""></span></span></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">روش کار:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">22 زن بهبود</span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> یا</span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">فته از کووید-19 شهرستان&shy; های آبادان و خرمشهر پس از فراخوان عمومی و گزینش در دو گروه 11 نفره</span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> شا</span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">مل گروه تمرین مقاومتی و گروه کنترل تقسیم&shy; بندی شدند. پروتکل تمرین مقاومتی به مدت هشت هفته و سه جلسه در هفته شامل هشت حرکت با شدت 40 تا 75% یک تکرار بیشینه اجرا شد. خون&shy; گیری در دو مرحله پیش و پس از اجرای پروتکل انجام گرفت. اندازه&shy; گیری سطوح آیریزین، فولیستاتین و </span></span>FGF21<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> به روش الایزا انجام شد و </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">داده</span></span><b>&shy;</b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">ها با استفاده از آزمون آماری کوواریانس (آنکوا) در سطح (</span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">0/05></span></span>P<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">)</span></span> <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">آنالیز گردید.</span></span><b><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Mitra""></span></span></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">یافته &shy;ها:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">مقایسه بین&shy; گروهی داده&shy; ها نشان داد که مقادیر آیریزین (0/05</span></span><span lang="FA" style="font-size:12.0pt"><span cambria="" style="font-family:">></span></span>p<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">)، فولیستاتین (0/05</span></span><span lang="FA" style="font-size:12.0pt"><span cambria="" style="font-family:">></span></span>p<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">) و </span></span>FGF21<span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> (</span></span>p<<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">0/05</span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">)</span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> گروه مقاومتی در مقایسه با گروه کنترل افزایش معناداری داشته است</span></span>. <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">همچنین</span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بررسی تغییرات درون&shy; گروهی آیریزین (05/0</span></span><span lang="FA" style="font-size:12.0pt"><span cambria="" style="font-family:">></span></span>p<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">)، فولیستاتین (05/0</span></span><span lang="FA" style="font-size:12.0pt"><span cambria="" style="font-family:">></span></span>p<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">) و </span></span>FGF21<span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> (05/0</span></span><span lang="FA" style="font-size:12.0pt"><span cambria="" style="font-family:">></span></span>p<span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">) نشان داد که بین میانگین قبل و بعد در گروه مقاومتی افزایش معنادار وجود دارد</span></span>.<span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Mitra""></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">نتیجه&shy; گیری:</span></span></b> <span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">به نظر می&shy; رسد تمرینات مقاومتی از طریق بازیابی توده عضلانی در </span></span><span lang="FA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">زنان</span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بهبود یافته از کووید-19 منجر به بهبود نیمرخ مایوکاینی می&shy; گردد.</span></span><b><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Mitra""></span></span></b></span></span></span></span></span></td> </tr> </tbody> </table> </div> <div style="text-align: justify;"></div> <div> <table align="left" hspace="0" vspace="0"> <tbody> <tr> <td style="padding: 0cm 12px; text-align: justify;" valign="top"><span style="font-size:10pt"><span style="line-height:110%"><span new="" roman="" style="font-family:" times=""><b><span style="line-height:110%">Introduction:</span></b> <span lang="EN" style="line-height:110%">Recently, performing regular sport activities has received attention due to the release of Myokines in reducing the complications caused by Covid-19, especially reducing inflammation and oxidative stress, rebuilding and repairing damaged tissues and reducing metabolic disorders. The purpose of this study was to determine the effect of eight weeks of selected resistance training on the levels of Irisin, Follistatin and FGF21 in women who recovered from Covid-19.</span><span style="line-height:110%"></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span new="" roman="" style="font-family:" times=""><b>Materials </b><b>and Methods</b><b>:</b> Upon a public call, twenty-two women who recovered from Covid-19 in Abadan and Khorramshahr cities were selected and divided into two groups of 11 people, including the resistance training group and the control group, . The resistance training protocol was implemented for eight weeks and three sessions per week, including eight movements with an intensity of 40 to 75% of a maximum repetition. Blood sampling was done in two stages before and after the implementation of the protocol. The measurement of the levels of the Irisin, Follistatin and FGF21 was done by ELISA method and the data was analyzed using the covariance statistical test (ANCOVA) at the (p<0.05) level.</span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span new="" roman="" style="font-family:" times=""><b>Results:</b> Comparison of the between groups data showed that the values of irisin (p<0.05), follistatin (p<0.05) and FGF21 (p<0.05) significantly increased in the resistance group compared to the control group. In addition, the examination of intra-group changes of irisin (p<0.05), follistatin (p<0.05) and FGF21 (p<0.05) indicated that there is a significant increase between the mean before and after implementation of the protocol in the resistance group.</span></span></span><br> <span style="font-size:10pt"><span style="line-height:normal"><span new="" roman="" style="font-family:" times=""><b>Conclusion:</b> It seems that resistance training leads to improvement of Myokine profile through the recovery of muscle mass in women recovering from covid-19.</span></span></span></td> </tr> </tbody> </table> </div> <div style="text-align: justify;"></div> کووید-19, آیریزین, فولیستاتین, FGF21, تمرین منتخب مقاومتی Covid-19, Irisin, Follistatin, FGF21, selected resistance training 1129 1139 http://journal.jmu.ac.ir/browse.php?a_code=A-10-754-1&slc_lang=fa&sid=1 Parisa Amiri Farsani پریسا امیری فارسانی 10031947532846007847 10031947532846007847 No Ph.D. Student in the Field of Physical Education and Sports Sciences, Science and Research Department, Islamic Azad University, Tehran, Iran دانشجوی دکتری تخصصی رشته تربیت بدنی و علوم ورزشی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران Farshad Ghazalian فرشاد غزالیان phdghazalian@gmail.com 10031947532846007848 10031947532846007848 Yes Associate Professor, Department of Physical Education and Sports Sciences, Science and Research Unit, Islamic Azad University, Tehran, Iran دانشیار گروه تربیت بدنی و علوم ورزشی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران Sara Mobarak سارا مبارک 10031947532846007849 10031947532846007849 No Assistant Professor, Department of Infectious Diseases, University of Medical Sciences, Abadan, Iran استادیارگروه بیماری های عفونی، دانشگاه علوم پزشکی، آبادان، ایران Esmat Radmanesh عصمت رادمنش 10031947532846007850 10031947532846007850 No Assistant Professor, Department of Physiology, University of Medical Sciences, Abadan, Iran استادیار گروه فیزیولوژی، دانشگاه علوم پزشکی، آبادان، ایران Mandana Gholami ماندانا غلامی 10031947532846007851 10031947532846007851 No Associate Professor, Department of Physical Education and Sports Sciences, Science and Research Unit, Islamic Azad University, Tehran, Iran دانشیار گروه تربیت بدنی و علوم ورزشی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران