Introduction: Due to importance of health pests and necessity of their control using of biological methods to protect the environment and ecology of beneficial insects, the purpose of this study was to present an overview of the natural enemies of pests and predators, as well as introduced three new predators' species in Iran.

 Methods: This study reviewed (review) using the key words such as: Predator, Nautral enemies , Biological control , in Databases of Ovid, Pub Med, Web of Science, Systematic Review and SID in site and out of the country during the years 1361 to 1391 (1981 to2012), in English and Persian language. In this study out of about 170 articles, 54 papers were selected the qualified sources and investigated.

 Results: To reduce health problems from pests and how to control it in human populations, biological methods can be used to simplify and have a lasting effects and the selected property as a suitable alternative to chemical control program. In the meantime, three health pest predators species, including; Eublepharis macularius, Hemiechinus hypomelas and, Scarites sp can be introduced as the most effective biological control in Isfahan province.

 Conclusion: Using of predators and recognition of new predators' species as biological methods instead of harmful chemical methods can have a healthy environment away from the dangers of application of chemical pesticides with the aim of providing a healthy society