Volume 10, Issue 4 (2-2024)                   J Jiroft Univ Med Sci 2024, 10(4): 1393-1402 | Back to browse issues page

‎ 20.1001.1.25382810.1402.10.4.3.2

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The Effect of Moderate Intensity Aerobic Exercise on Serum Levels of Interleukin-6, Interleukin-10 and C-reactive Protein in Patients Recovered from Covid-19
Davar Rezaeimanesh1 , Mohamad Kogani2
1- Assistant Professor, Department of General Courses and Basic Sciences, the College of Economics and Management, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran , davarrezaee@yahoo.com
2- Research center for Environmental Contaminants (RCEC), Abadan Universiey of Medical sciences, Abadan, Iran
Abstract:   (1906 Views)
Introduction: Sports activity is one of the non-invasive ways to rehabilitate and prevent complications and consequences of diseases related to Covid-19. The purpose of this study was to investigate the effect of moderate intensity aerobic exercise on the serum levels of interleukin-6, interleukin-10 and C-reactive protein in patients recovered from Covid-19.
Materials and Methods: For this purpose, 24 men recovered from Covid-19 were voluntarily selected and placed in two groups of experimental (12 people) and control (12 people) in a simple random manner. The experimental group participated in an eight-week aerobic training program, three sessions per week, each session lasted about 40 to 55 minutes with an intensity equal to 60 to 80% of the maximum heart rate. Serum levels of IL-6, IL-10 and CRP (before and 48 hours after the protocol) were measured. The data was analyzed using the covariance statistical test (ANCOVA) at the (p<0.05) level.
Results: The results showed that aerobic exercise did not lead to a significant change in the serum levels of IL-6 (p>0.05) and IL-10 (p>0.05) in the experimental group compared to the control group; however, it caused a significant decrease in the serum levels of CRP (p<0.05) in the experimental group. In addition, examining intra-group changes in IL-10 and CRP indicated that there is a significant change between the mean score before and after implementation of the protocol in the experimental group (p<0.05). While there was no significant difference between the before and after values in IL-6 (p<0.05).
Conclusion: Based on the results of this study, aerobic exercises can regulate and balance anti-inflammatory and inflammatory cytokines and adjust the amount of C-reactive protein through the recovery of physical fitness in patients who have recovered from Covid-19.
Keywords: Covid-19, Interleukin-6, Interleukin-10, C-reactive protein
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Type of Study: Research | Subject: Medical Sciences / Sports Medicine
Received: 2023/10/3 | Accepted: 2025/01/17 | Published: 2024/03/10
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